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Whilst glycine is the simplest amino acid found in our body, it is also one of the most crucial because it synthesises proteins. To put it simply, we are unable to live without it. Although it is found in many of the foods we eat, more often than not, we still do not get as much as we need. In this blog, Human Performance Hub explores whether glycine is good for building muscle and why athletes use glycine as a supplement. 

So, is glycine good for building muscle? Yes. Glycine is fantastic for building muscle because it synthesises proteins and plays a vital role in the creation of creatine and collagen. Both of these lead to an increase in growth hormone release which ultimately builds muscle.  

Keep reading to find out more about how glycine builds muscle and why athletes use glycine to improve physical performance. 

 

Does Glycine Build Muscle? 

Yes. Glycine is a huge contributor to muscle growth because it plays a vital part in the creation of creatine and collagen, both of which provide strength for your muscles. Studies show that a high dose of glycine intake can cause an increase in growth hormone release. This post-workout boost can help stimulate protein synthesis, build muscle and promote faster recovery. 

As a non-essential amino acid produced by the body, glycine synthesises proteins and plays a crucial role in the creation of

Creatine 

Glycine is one of three amino acids that your body uses to make a compound called creatine. Creatine provides your muscles with energy to perform quick, short bursts of activity, such as weightlifting and sprinting. On top of this, when creatine is combined with resistance training, studies show that it increases muscle size, strength and power. Bodybuilders use creatine supplementation to gain both muscle strength and mass. 

Collagen 

Collagen is a structural protein containing high amounts of glycine. In fact, every third to fourth amino acid in collagen is glycine. As the most abundant protein found in your body, collagen provides strength for your muscles, skin, cartilage, blood, bones and ligaments.

Supplementing with collagen has even been shown to benefit skin health, relieve joint pain and prevent bone loss. As a result, it is crucial that you get enough glycine to support your body’s production of collagen. 

Why Do Athletes Use Glycine? 

Athletes can gain a competitive edge by supplementing with glycine in the following ways

Performance 

Glycine has been proven to help with muscle gain. Experiments show that taking a single bolus with a high dose (22.5 grams) of glycine causes a 60% surge in growth hormone release from the pituitary gland in under five minutes. This rapid growth hormone boost post-workout helps build muscle and promote recovery whilst stimulating protein synthesis. Even smaller doses of four, eight and twelve grams will increase serum levels of growth hormones. 

When it comes to anaerobic performance, glycine has not been studied much. However, a supplemental form of glycine known as glycine-propionyl-L-carnitine has been shown to enhance peak power production and reduce lactate build during repeated, high-intensity sprints when taken 90 minutes pre-workout. 

Recovery 

Glycine and green tea have been proven to be effective in recovery after injury. The combination may even get you back on the track or field sooner than you had planned. Interestingly, a study was conducted using mice with achilles tendinitis. The mice who were given a glycine and green tea cocktail had greater tissue recovery, more collagen synthesis and lower inflammation. 

Therefore, it is clear that the combination of these two supplements produce a faster and more salient remodelling process after injury. 

More Benefits Of Glycine

Here is a list of some of the many other benefits of taking glycine supplements:

  • Improves sleep
  • Boosts metabolism
  • Improves heart health
  • Brain food
  • Lowers inflammation 

To read more about these benefits, take a look at our blog on The Top 7 Benefits Of Glycine Powder. 

How Much Glycine Should I Take To Build Muscle? 

While technically “non-essential,” the amounts of glycine we synthesise, plus dietary glycine, may fall short of the amount we need for optimal metabolic function. For all of the necessary metabolic functions to occur, we need 15 grams of glycine, however we only produce around 2.5 grams per day. This leaves another 12 grams of glycine intake needed to function at our best. Studies indicate that other sources, like dietary glycine do not meet this need. 

This is where our glycine powder at Human Performance Hub comes in. We recommend that you consume 3 grams (approximately 1/2 teaspoon) with water or any other beverage per day or as directed by your health care practitioner. 

 

How Do I Take Glycine? 

Glycine is readily available as a dietary supplement in capsule or powder form. If you do not like taking pills, the powder form dissolves easily in water and has a sweet taste. 

Fun fact – the name glycine is derived from the Greek word for ‘sweet’ (glykys) because of its sweet taste. 

Since glycine is so sweet tasting, it is easy to incorporate into your diet by adding it to:

  • Coffee and tea
  • Soups 
  • Oatmeal
  • Protein shakes
  • Yogurt 
  • Pudding

Is It Safe To Take Glycine?

As with any supplements, glycine is safe to consume in appropriate amounts. Studies have used up to 90 grams of glycine per day over several weeks without serious side effects. For comparison, the standard dose used in studies is about 3-5 grams per day.  

How Much Glycine Should You Take Per Day?

Start with 1 scoop of glycine powder mixed with water and taken after your evening meal. This dosage can then be increased to a maximum of 30g if you do not see any benefit from a single scoop, remember to monitor the effects and response you get from taking the supplement. 

Always talk to a qualified practitioner if you need further specific advice for your health. 

Glycine Powder at Human Performance Hub

Now that you know how glycine builds muscle, take a look at our extensive range of Glycine Powder supplements at Human Performance Hub

Whether you’re looking to improve your physical performance by building and strengthening your muscles or you’re simply looking to improve your sleep, we have something for everyone’s needs. 

Take a look at our range online today, or get in touch with us for tailored advice.

Human Performance Hub Glycine Powder

 

Human Performance Hub Berberine Complex

Berberine has a number of health benefits. In fact, it’s been used in traditional Chinese medicine for hundreds of years. But, one of the lesser known uses of berberine is for exercise and performance. In this article, we look at how berberine impacts exercise, in particular how it can help to build muscle and support fat loss.

So, does berberine affect exercise? Berberine doesn’t directly affect exercise but may have an impact on results. For example, berberine helps to increase energy, encourage fat loss and energy storage in the muscles, and helps to reduce muscle damage associated with intense workouts. This is beneficial for those looking to build muscle.

Read on to learn more about the relationship between berberine and exercise with Human Performance Hub. 

Does Taking Berberine Impact Exercise?

There’s limited evidence to suggest that berberine directly impacts exercise. It may, however, impact results. Research into the effects of berberine on metabolism, glucose intake and recovery suggests that it increases energy levels. It may also encourage both fat loss and energy storage in the muscles, making it an ideal supplement for bodybuilders.

 

Studies found that berberine downregulates genes that are responsible for cholesterol absorption into the intestines, preventing fat accumulations (1, 2). It also activates brown fat thermogenesis which can improve energy levels whilst limiting weight gain.

 

Additionally, berberine may benefit recovery from exercise in that it possesses antioxidant and anti-inflammatory properties. Further to this, berberine may reduce oxidative stress markers, combatting the damage associated with intense workouts.

Does Berberine Affect Muscle Gain?

Berberine has a similar action to insulin, improving glucose uptake into cells. For those looking to build muscle, this boosts energy production, helps to prevent cell breakdown and increases energy storage, all of which are central to building muscle mass.

Does Berberine Affect Testosterone?

Previously, research suggested that berberine could lower testosterone levels in men. However, more recent studies found that berberine does not lower testosterone in men. Although, trials found that berberine does lower testosterone in women that have polycystic ovary syndrome

Studies are inconsistent on this matter, with some researchers suggesting that the discrepancies between men and women may simply be down to dosage, or has some unknown relation to polycystic ovary syndrome.

Does Berberine Speed Up Metabolism?

Yes, berberine is thought to speed up metabolism and reduce blood glucose. This limits the amount of glucose and lipids that get stored in the body, therefore assisting weight/fat loss.

Should You Take Berberine Before or After a Workout?

It doesn’t matter too much whether you take berberine pre-workout or post-workout, but note that it has a half-life of around 5 hours. The main thing to consider when taking berberine is that it shouldn’t be consumed on an empty stomach as it risks hypoglycemia. As such, it’s best to take it with a meal – most choose to take one serving with breakfast, and a second serving with their evening meal. This also accounts for the 5- hour half-life, allowing you to make the most of the supplement.

How Much Berberine Should I Take

How much berberine you take depends on your goals. But, if you’re looking to build muscle mass, most bodybuilders take around 1-1.5g of berberine per day, divided into 2-3 servings.

Health Benefits of Taking Berberine

Aside from fat loss and metabolic benefits, berberine has a number of other health benefits, including:

Heart Health

Research suggests that berberine may be beneficial in a number of heart health concerns, including heart disease – the number one cause of death worldwide.

According to a review of 16 studies, berberine may:

  • Lower total cholesterol
  • Lower LDL (bad) cholesterol
  • Lower blood triglycerides
  • Increase HDL (good) cholesterol

 

Further to this, diabetes, high blood sugar levels, and obesity are also major risk factors for heart disease, all of which seem to be improved with berberine.

Other health benefits of berberine include:

  • May help to improve symptoms of depression
  • Shown to have potent antioxidant and anti-inflammatory properties (1, 2, 3)
  • Reduces the growth of harmful microorganisms, including bacteria, viruses, and fungi (1, 2, 3)
  • May reduce fat build-up in the liver

Top Quality Berberine at Human Performance Hub

Find top quality berberine supplements at Human Performance Hub. Choose between Berberine Complex Vegetarian Capsules, or Gluco Support Capsules which contain berberine, cinnamon extract, banaba extract and ginseng.

Alternatively, if you’re unsure what you need to achieve your goals, contact us today for tailored advice.

Human Performance Hub Berberine Complex

 

FAQs

What is Berberine?

Berberine is a bioactive compound found in several different plants. Technically an alkaloid, it has a yellow colour and is also often used as a dye. This supplement has a long history of use in traditional Chinese medicine and is today most commonly used for managing diabetes, cholesterol and high blood pressure. 

 

What are the Side Effects of Berberine?

The potential side effects of taking berberine include:

  • Diarrhoea
  • Constipation
  • Excessive gas
  • Upset stomach
  • Hypoglycaemia

 

Who Should Not Take Berberine?

Adults that take other medication, such as insulin, liver, clotting and pressure medication should consult a doctor before proceeding. Infants, children and breastfeeding or pregnant women should avoid taking the supplement altogether.

bananas

If you’ve ever wondered whether potassium calms anxiety, you’ve come to the right place. In this blog, Human Performance Hub explores whether or not potassium calms nerves and how it works within the body. 

So, does potassium calm nerves? Potassium has been shown to calm nerves, anxiety and depression. It does this by regulating a range of hormones produced as a result of stress, like cortisol and adrenaline. Studies have shown that potassium activates neurons involved in positive thoughts and feelings. 

Read on to learn more about how potassium helps with nerves and the many more benefits of consuming this mineral. 

 

Can Potassium Help With Nerves? 

Yes. Ingesting potassium assists with regulating a variety of hormones in your body, especially those produced as a result of stress, such as cortisol and adrenaline. This helps reduce any feelings of anxiousness or tension that you may be experiencing. 

Potassium and Anxiety

A common cause of anxiety is having a poor diet. When you lack a particular vitamin or mineral, your system can be hugely affected. In relation to potassium, low levels can cause mental fatigue, stress and anxiety. The best way to overcome this is to eat a well balanced diet with plenty of natural foods.This can help you overcome your anxiety. 

Potassium and Depression

Low potassium levels have also been associated with an increase in mood disturbances and depression. A 2008 study published in the British Journal of Nutrition, examined the relationship between potassium and mood. They found that a high-potassium diet helped to relieve symptoms of depression and tension. These results show that potassium is extremely effective in generally uplifting our mood. 

What Is Potassium and How Does It Work in the Body?

Potassium is a mineral that every cell in your body needs. It helps just about everything in your body, including your brain, nerves, kidneys, heart and other organs. As an electrolyte, potassium helps to manage how much water is in your body. It also helps to keep up your body’s electrical system whilst moving nutrients into your cells and taking waste out. Additionally, potassium keeps your body’s sodium levels in check. 

Other Health Benefits of Potassium

Potassium is incredibly important because it helps our hearts, kidneys and other organs work normally. Here is a list of the many benefits of potassium

Increases Brain Function

High potassium levels act as a vasodilator, allowing blood to move more easily through the blood vessels. This blood carries oxygen to the brain, which increases your activity levels and cognitive abilities. 

Normalises Blood Pressure

Potassium works to balance blood pressure and counteract the effects sodium has on raising it. This helps to reduce the risk of hypertension and heart disease

Increases Metabolism

Potassium helps your body extract nutrients from what you eat and helps to break down and process these nutrients. It also plays an important role in synthesising protein and metabolising carbohydrates. 

Improves Muscular & Heart Health 

A diet that is adequate in potassium helps maintain strong muscles. Potassium helps muscle tissue grow properly and is also involved in the electrical signals sent by muscles. This lets them contract properly. 

Potassium is also important for a healthy heart, as its movement in and out of cells helps maintain a regular heartbeat. 

Aids Nervous System 

Your nerves send messages to various parts of your body. Potassium helps to make the transportation of these signals easier and more efficient. This improved functioning helps your muscles perform better. 

Helps Prevent Kidney Stones 

Kidney stones are ‘hard stones’ made from calcium in your urine. One form of potassium, potassium citrate, binds up this calcium. This helps prevent crystals from forming that could become kidney stones. 

Helps Regulate Serotonin

A study in the journal ‘Nature Neuroscience’ investigated the role of potassium in the regulation of serotonin, the neurotransmitter primarily targeted by antidepressants. The results showed that potassium appears to act as a facilitator in ensuring the brain’s ability to properly utilise serotonin. 

Potassium counteracts the thoughts and feelings associated with depression and instead activates neurons involved in positive thoughts and feelings. Without the electrical charge sparked by potassium, neurotransmitters like serotonin cannot be utilised to make us feel better. This explains why even a slight decrease in potassium levels can result in significant feelings of anxiety. 

Helps Prevent Osteoporosis 

With this condition, bones can become less dense which makes them more likely to break. Foods rich in potassium can slow this down. Potassium does this by cutting down on how much calcium leaves your body in your urine, keeping this calcium around helps to keep bones strong. 

Helps Regulate Fluid Balance 

The amount of water in your intracellular fluid (water found inside your cells) and extracellular fluid (water found outside your cells in areas such as your blood and spinal fluid) is directly affected by your electrolytes, potassium and sodium. Potassium is the main electrolyte in the intracellular fluid and determines the amount of water inside the cells. Sodium is the main electrolyte in the extracellular fluid and determines the amount of water outside the cells. It’s therefore crucial that you consume the right electrolytes, including potassium. 

How Much Potassium Do You Need? 

Adults (19 to 64 years) need 3,500mg of potassium a day. You should be able to get all the potassium you need from your daily diet. 

Below, we’ll explain what happens if you get too much or too little potassium in your diet:

Too Much (Hyperkalemia)

A healthy individual will naturally pass extra potassium out of the body, so most people don’t actually have to worry about getting too much potassium. However, if something makes it hard for your body to get rid of potassium, it can cause hyperkalemia. Those at risk include people with kidney conditions and those who take certain types of medicines. 

Bear in mind that hyperkalemia doesn’t always cause symptoms. It can however make your muscles feel weak or cause nausea. 

Too Little (Hypokalemia) 

Not enough potassium can make your muscles weak. Common symptoms include cramps, constipation and fatigue. It is possible to have hypokalemia because you don’t get enough potassium from food but it’s more likely to happen with conditions like Crohn’s disease or ulcerative colitis, if you have severe vomiting or diarrhoea. 

If you have low potassium, foods are a great natural source. Your doctor may even recommend that you supplement with potassium. 

To find out how much potassium is in the fluid part of your blood, the NHS has a potassium test

Examples of Potassium Rich Foods

Here is a list of foods high in potassium: 

  • Acorn squash
  • Bananas
  • Dried fruits (apricots, peaches, prunes, raisins)
  • Milk
  • Salmon
  • Baked potatoes (skin on)
  • Tuna 
  • Yogurt 
  • Spinach
  • Avocado
  • Coconut water
  • Lentils 
  • Melon 
  • Mushrooms
  • White beans 

Potassium Supplements at Human Performance Hub 

Now that you are aware of the many benefits of potassium consumption, take a look at Human Performance Hub’s range of potassium supplements

From our Electrolyte Hydration Complex formula to our Metabolic Multi Complex vitamins, there is something to suit all individuals. Designs For Health fuel our products and only contain high-quality ingredients, all at a great price. 

Human Performance Hub Electrolyte Hydration Complex

 

Get in touch with us today to discuss your specific requirements. 

lemon water

Some detoxes appear to be more legitimate than others, such as simple lemon water, but how effective is it actually? In this article, we take a look into lemon water detoxes and explore how consuming lemon water may benefit the rest of the body. 

So, does lemon water detox your liver? Experts disagree on whether lemon does indeed detox the liver, however studies suggest that lemon water may improve liver function. Lemon water also holds a number of other benefits such as boosting the immune system, aiding digestion and helping with weight loss.

Read on to learn more about lemon water detox and how consuming lemon water benefits the body as a whole.

Does Water With Lemon Detox Your Body?

A number of citrus fruits, including lemon, can be added to water to help detox the liver and improve liver function. Studies show that the antioxidants in lemon reduce inflammation, remove free radicals and improve the body’s ability to process glucose. It is also thought that these antioxidants may lower blood sugar and cholesterol levels.

Further to this, research claims that the nutrients from lemons may decrease fat storage in the liver and may reduce chronic alcohol-induced liver damage. Scientists explain that lemons contain vitamin C, flavonoids, carotenoids and other bioactive compounds that fight oxidative damage and protect the liver. 

Additionally, studies have found that the liver produces more enzymes in the presence of lemon when compared to other food and drink. These enzymes are essential to simulate accelerate and catalyse various chemical reactions throughout the body,

That being said, most research into the effects of lemon on the liver has been carried out on animals, therefore more research is needed to fully understand their relationship in humans.

How Much Do You Need to Drink?

When detoxing with lemon water, it is advised to drink ½ to 1 whole lemon juice mixed with water every day. But, if you’re not such a fan of lemon, other options are available to similar effect.

Other Options

  • Plain water – water is the best way to recharge and maintain good liver health
  • Other citrus fruits – e.g. grapefruit juice
  • Teas – e.g. lemon and ginger, peppermint or green tea
  • Turmeric spice – may decrease inflammation and assist with liver repair
  • Ginger juice water – thought to protect the liver from toxins and reduce inflammation

Other Health Benefits of Drinking Lemon Water

Research suggests that detoxing with lemon may have a positive impact on overall health and wellbeing, not just on the liver. These benefits include:

Boosts the Immune System

The consumption of highly acidic foods, such as lemon juice, contributes to an acidic stomach environment that may deter pathogens from gaining a foothold and causing illness. Further to this, lemons have antioxidant properties which help to protect the body from disease.

Aids Digestion

Lemon water helps the body to digest food. The citrus flavonoids aid the stomach in breaking down food, thus helping overall digestion. This appears to be particularly beneficial when the lemon water is warmed. 

Improved Hydration

Lemon is not in itself associated with hydration, however many people struggle to consume enough water each day to stay properly hydrated. Consuming water with a flavour such as lemon may make drinking water more appealing, thus improving hydration.

Promotes Regular Bowel Movements

Along with helping the liver and the gut, lemon water may also encourage more regular bowel movements. Like with improved hydration, lemon isn’t inherently good for bowel regularity, drinking more water is. 

Prevents Kidney Stones

Similarly, the boosted hydration as a result of drinking more water, as well as the acid from the lemons can help to prevent kidney stones. The water flushes out the kidneys and the lemon acid reacts with the chemicals in the kidneys to help keep stones from forming.

Boosts Metabolism 

A lemon water detox has a number of benefits but it is particularly useful when consumed first thing in the morning as it can jump start your metabolism. This helps to maintain a healthy weight and be active. This is most effective when consumed cold. The body needs to warm the water to temperature during digestion.

Reduces Appetite

For those looking to lose weight, lemon water may help to reduce appetite. Studies suggest that the polyphenols in lemon may help to prevent weight gain, whilst the consumption of water helps you to feel more full. This reduces the amount of food needed to feel satisfied. 

Like lemons, limes also have great health benefits. Check out our recent blog for more information about how limes can boost your energy, immunity, gut health, and decrease belly fat. 

Takeaway

We hope that we’ve sold you on the huge health benefits to both the liver and the body as a whole that lemon water provides. Simply mix lemon juice (from a real lemon, not from a bottle!) with at least 200 ml of water. It’s your choice whether or not to warm the water through, but a number of experts recommend heating the water to maximise the results.

Why not try these supplements for an additional digestive boost with complementary benefits?

1 HPH Fibre + 

Human Performance Hub Fiber - Apple Pectin Fiber + would be ideal for anyone who doesn’t get adequate fibre from their diet or has stomach issues (bloating, gas, constipation). This is particularly suitable for people looking to avoid grains whilst getting fibre.

 

2 ATP Lab Glutamed 

ATP Lab Glutamine and glycine

Glutamed can benefit you if you are looking to support your gut health and immune support. Glutamine could also be used to down-regulate your nervous system after being ramped up for intense training and/or before sleep, which will aid your body in recovery.

3 GI Regenerate

Human Performance Hub GI Regenerate

GI Regenerate is an all-around sufficient supplement to support and improve your gut health. Fulled by Designs for Health G.I Revive powder.

 

Alternatively, you can get in touch with us to arrange a consultation. 

coffee on table

L-Carnitine is a molecule found in the body, used in numerous bodily processes. It is a combination of two amino acids which, when mixed together, create a single compound. Primarily, this supplement is associated with fat loss and brain function of which there are a number of studies to support this. Recently, however, people have started taking L-Carnitine with coffee to maximise the benefits. In this article, we explore whether or not it’s worth mixing L-Carnitine with coffee and discuss these potential benefits.

 

So, can I take L-Carnitine with coffee? Yes, you can mix L-Carnitine with coffee. It is often recommended to take with your morning coffee for best results. In fact, some experts recommend this method of consumption as the caffeine, alongside the time of day taken, may increase the benefits of taking L-Carnitine. 

 

Read on to learn more about L-Carnitine coffee, why you should do it, and how to make it. We also go into further detail about the general benefits of taking L-Carnitine supplements.

 

Can You Mix L-Carnitine with Coffee?

L-Carnitine is naturally found in the body and in some foods, but to really reap the benefits, most people need to supplement their intake of L-Carnitine. Some people choose to mix L-Carnitine with coffee as caffeine can significantly improve the benefits of taking this supplement. This is due to a number of factors:

  1. Most people take their coffee first thing in the morning. When mixing with L-Carnitine, this allows you to leverage the energy provided by both the caffeine and the supplement throughout the day.
  2. L-Carnitine can help to stabilise the energy gained from coffee and may help to reduce the coffee shakes!
  3. L-Carnitine coffee provides energy without needing to eat additional food. When eating this additional food, energy is gained from it, and any surplus is stored for later. With L-Carnitine, the energy comes from stored fat, making it great for weight or fat loss.
  4. Some studies show that L-Carnitine works best when consumed in smaller amounts alongside foodstuff. Mixing it with coffee gives you a bit of supplement with each sip, rather than in one large dose. 

 

When to Take L-Carnitine Coffee

Most people recommend taking L-Carnitine mixed into their morning coffee. This is because one of the key benefits of taking the supplement this way is to boost energy. There’s no point in waiting to take it with lunch or dinner if your primary aim is an energy boost (unless you need a mid-afternoon pick-me-up!). 

 

Furthermore, some people recommend taking L-Carnitine coffee in the morning on an empty stomach. This is to allow the compound to more rapidly digest and activate the benefits sooner. 

 

How to Take L-Carnitine With Coffee

If you want to add L-Carnitine to coffee, simply take your L-carnitine capsule with your morning coffee. 

 

If you’re taking L-Carnitine coffee for exercise purposes, it’s important to take it around an hour before working out. For other benefits, it can be taken at your convenience, although it’s best to have it early in the morning. 

 

Benefits of L-Carnitine

We’ve touched on the benefits of taking L-Carnitine with coffee, but there are a world of other benefits associated with the supplement. These include:

Weight/Fat Loss

Research is divided on the effects of L-Carnitine on weight loss, however, in theory, it supports weight loss by producing energy from existing fat stores. Learn more about this in our blog, What are the Benefits of L-Carnitine? Where we go into more detail about this particular benefit. 

Supports Brain Function

We’ve already discussed how L-Carnitine is great for energy production, but it may also be effective in supporting general brain function. Research indicates that the ALCAR form of L-Carnitine may help against age-related mental decline. Additionally, it may support and improve markers of learning

Furthermore, some studies indicate that taking L-Carnitine daily helps to reverse the decline in brain function in association with brain diseases such as Alzheimer’s. In some cases, it may also protect the brain from cell damage. 

Supports Heart Health

Some studies have shown that L-Carnitine may help to reduce blood pressure and support the inflammatory processes associated with heart disease. In fact, one study reported that just 2 g per day resulted in an almost 10-point drop in systolic blood pressure – an important indicator of heart health.

Boosts Exercise Performance

Evidence is mixed in relation to L-Carnitine’s relationship with exercise performance. However, it may benefit the following factors, especially when taken with caffeine:

 

 

How Much L-Carnitine Should You Take?

If you’re ever unsure about supplement dosage, consult the instructions on the packaging, or speak with your doctor or functional medicine practitioner. As a rule of thumb, however, experts suggest the following dosages for different forms of L-Carnitine:

 

  • Acetyl-L-Carnitine: 0.6-2.5 g per day
  • L-Carnitine L-Tartrate: 1-4 g per day

L-Carnitine Supplements at Human Performance Hub

At Human Performance Hub, we aim to empower people with knowledge, personalised services, and quality supplements to make informed decisions to improve their health.

We stock a range of L-Carnitine supplements to help support your goals. Choose from

 

 Carnitine Complex Vegetarian Capsules

Acetyl L Carnitine UK Vegetarian Capsules 

Alternatively, get in touch with our experts today for more information and advice on health supplementation. 

Glycine is a naturally occurring amino acid that the body uses to create proteins. This is needed for the growth and maintenance of tissue, for the production of hormones and enzymes and for a number of other health benefits. In this article, we discuss the top 7 benefits of glycine to help you understand why supplementing with glycine can be so valuable.

So, what are the top 7 glycine benefits? Glycine is an amino acid that contributes to a number of health benefits including the production of serotonin and glutathione, improving sleep, supporting athletic performance, reducing the risk of heart disease and more.

Read on to learn more about what glycine is, what it does and how much should be taken per day to receive the benefits.

What is Glycine and What Does it Do?

Glycine is an amino acid that naturally occurs in the body. It can also be consumed in food such as meat, fish, dairy, legumes, or as a supplement. It is a building block for making proteins in the body and is involved in transmitting chemical signals to the brain, as well as stimulating the production of serotonin, the “feel-good hormone”. 

Further to this, glycine is also a key component of collagen, the protein that gives structure to the bones, skin, muscles and connective tissues. Other benefits and uses for glycine (in which we will go into more detail later) include:

  • Mood and memory
  • Sleep
  • Needed to produce an antioxidant
  • Improves brain-muscle performance
  • Decreases the risk of heart disease
  • Protects the liver from alcohol damage
  • Aids in the management and prevention of diabetes

Top 7 Benefits of Glycine

Below we go into more detail about the top 7 glycine benefits.

Powerful Antioxidant

Glycine is one of three amino acids that the body uses to create glutathione, a powerful natural antioxidant. Glutathione protects the cells against oxidative damage caused by free radicals (thought to underlie many diseases). 

If the body doesn’t naturally produce enough glycine (or other amino acids), less glutathione will be produced. This may negatively impact how the body handles oxidative stress. Over time, the body begins to produce less glutathione, therefore, it’s important to supplement glycine levels with diet or supplements. 

Decreases Risk of Heart Disease

As a powerful antioxidant and anti-inflammatory, glycine may help to reduce the risk of heart disease. In fact, a study in the Journal of the American Heart Association found that those with a higher plasma glycine level had a reduced risk of heart attack and had a more favourable heart disease profile.

Improves Brain-Muscle Performance

Glycine plays a part in the creation of creatine, a substance that provides muscles with the energy needed for short bursts of strength and speed. It is a particularly popular benefit for athletes. 

It can also provide the brain with energy which can help with cognitive functions such as short-term memory and reasoning. 

May Improve Sleep Quality

Amino acids like glycine are thought to have a calming effect on the brain and may help people to fall asleep easier. It may also help people to  stay asleep by lowering their core body temperature. 

Further to this, research has shown that glycine can help to lessen daytime sleepiness and improve cognition.

Aids in Diabetes Management and Prevention

It is thought that glycine may aid in the management and prevention of diabetes as glycine stimulates a gut hormone that increases the ability of insulin to remove glucose from the bloodstream. 

Protects the Liver from Alcohol Damage

Whilst there are a number of health benefits to reducing alcohol intake, glycine has been shown to reduce the harmful effects of alcohol on the liver by preventing inflammation. 

It may also reduce concentrations of alcohol in the blood by stimulating the metabolism of alcohol in the stomach, rather than in the liver which may prevent the development of fatty liver and alcohol cirrhosis.

Further to this, glycine may also aid in the reversal of liver damage and improve the recovery process. In a study, liver cell health returned to baseline 30% faster in those supplemented with glycine than those without. That being said, more research is needed in this area.

Impacts Mood and Memory

Glycine stimulates the production of serotonin, the “feel-good” hormone that helps to improve mood, memory and cognitive thinking. In fact, some people refer to glycine as a “natural antidepressant”. However, it’s important to note that these benefits are typically short-lived.

How Much Glycine Should You Take Per Day?

We recommend starting with 1 scoop of glycine powder mixed with a bit of water and taken after your evening meal. This dosage can be increased to a maximum of 30g if you do not see any benefit from a single scoop, but be sure to monitor the effects and response you get from the supplement.  Talk to a qualified practitioner if you need further specific advice for your health. 

Glycine Powder at Human Performance Hub

At Human Performance Hub, we offer our own Glycine Powder supplement to help improve your performance, encourage better sleep, boost your mood and assist with a number of other health benefits. Take a look at our range online today, or get in touch with us for tailored advice.

 

Optimal digestion is challenging to achieve if the digestive function is compromised. It can result in a lack of essential nutrients absorbed from food. There are a number of conditions that may impact digestion, meaning food is not broken down properly, and nutrients are not absorbed. This is where Digestive Enzymes can aid the digestion process.

What Are Digestive Enzymes and Digestzymes?

Digestzymes combine digestive enzymes and betaine hydrochloride to maintain optimal digestion of proteins, fats and carbohydrates. The ingredients included in Digestzymes can alleviate the symptoms of digestive problems after eating, including gas and bloating, diarrhoea, occasional constipation and a feeling of fullness with smaller meals. As well as digesting the food, this blend also supports nutrient absorption.

What Are the Ingredients in Digestzymes?

Digestzymes contain a blend of digestive enzymes to aid the digestion process. Ingredients include:

  • Betaine HCI – HCI, also known as gastric acid, is an essential part of digestion and nutrient absorption in the body. It modulates acidity levels, creating an appropriate alkaline environment for the optimal efficiency of pancreatic enzymes. 
  • Pancreatic Enzymes – Required for the proper digestion and absorption of food, enzymes produce lipases, proteases and amylases to break down fats, proteins and carbohydrates. 
  • Ox Bile Extract – Originating in the liver, bile is a complex aqueous secretion that contains key components for proper digestion and supporting fat emulsification.
  • Dipeptidyl Peptidase IV (DPP IV) – This enzyme has the potential to aid in the digestion of food-derived opioids peptides, including those found in casein, wheat, and soy.

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What is the Recommended Dosage of Digestzymes?

The recommended starting dosage of Digestzymes is 2 capsules consumed in between a solid meal (eating half the meal and having 2 – 4 caps and then continuing with the rest of the meal), or follow directions from your healthcare practitioner. 

Who Would Benefit from Digestzymes?

People who produce too little gastric acid would benefit from the Betaine HCI part of Digestzymes. Too little gastric acid can lead to heartburn, nausea and hair loss, amongst other symptoms. Digestzymes can alleviate or remove these issues by balancing the body’s gastric acid levels. There are also other symptoms and conditions that Betaine HCI can positively impact, including stress, ageing and certain diseases. 

Individuals suffering from Pancreatic Insufficiency (EPI), a condition where the pancreas does not produce enough enzymes to digest food, would benefit from the pancreatic enzymes included in Digestzymes. This blend would positively affect conditions like diabetes, celiac disease, IBS and many more

The liver, gallbladder and gut microbiome problems can affect the body’s natural bile balance. Conditions that could benefit from the ox bile extract included in Digestzymes include bile acid diarrhoea, liver issues and metabolic disorders. People lacking digestive enzymes may experience sensitivities and discomfort when eating particular foods, meaning they should reap the benefits of the Dipeptidyl peptidase IV included in Digestzymes. 

Instagram Q&A: Should Digestzymes Be Taken All Year Round?

As part of our Instagram Q&A series (you can submit a question here), our founder, Roan Heming, gives his thoughts on whether digestive enzymes should be taken all year round.

You can view the video below:

If you can’t play the video for any reason, here is Roan’s answer:

“So, I would need further insight into why you started taking digestive enzymes to provide a fully accurate answer. I can completely understand, as this is one of the things I recommend to my clients off the bat; we are under so much more stress and strain than ever before, and, in turn, this lowers our stomach acid and makes it harder for us to break down food and absorb the nutrients that we need.

Digestive enzymes are anti-inflammatory. You will see improvements with bloating and gas, such as burping and passing of gas and even heartburn. It will support proteins, fats and carbs breakdown, helping with the absorption. And, remember, we are what we absorb. The two ingredients that I would want you to make sure that you’re having with the product are HL, having a minimum of two milligrams, and ox bile, which will help with the fat breakdown into smaller molecules and be absorbed in the lower intestine. Just remember, proper digestion is essential to our health. It can help with energy levels, skin, nails, mood, gut issues and, in turn, fat loss.”

What are the Best Foods to Eat for Digestive Health?

Many foods can be good for digestive health, and choosing items high in fibre and water is essential. Foods that are easy to digest, such as fruits and vegetables, are also beneficial. Avoiding processed foods and eating a balanced diet will help keep your digestive system healthy. Exercise and stress reduction can both also help improve digestion. If you have digestive problems, be sure to speak with your doctor or a registered dietitian to determine which foods work best for you.

How can you supplement with Digestzymes?

If you’re struggling to digest certain foods, supplementing with digestzymes may be helpful. These enzymes can be found in supplements, making them easy to incorporate into your diet. If you have any digestive issues, talk to your doctor or functional medicine practitioner about whether digestzymes might be right for you.

Digestzymes Supplementation at Human Performance Hub

Human Performance Hub provides only the best quality supplements on the market. Our Digestzymes help supports your body and a healthy digestive system by breaking down proteins, fats and carbohydrates.  Your cells are built from and are fueled by the nutrients you consume, and the classic phrase “you are what you eat” isn’t too far from the truth, but what is more accurate, “you become what you eat and absorb”.

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For more information on our supplements or to find the right one, contact a member of the Human Performance Hub team. 

Further Reading

Is gut health something you’d like to explore in more detail? Our articles and resources on the subject can be found here: 

🔗 The Gut – Health Connection: What you Need to Know

🔗 L-glutamine benefits for your gut, brain, muscles and more…

🔗 Foundation Series: Gut and Brain – The Immune system

🔗 Leaky Gut, Gluten, and Inflammation: What’s the Connection?

🔗 Resource: GI Regenerate

🔗 Resource: GI Microbial

 
 

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Essential choline provision for brain health, cognitive function, and more.

GPC supplementation is a breakthrough compound that has many research-backed benefits. In this guide, we walk you through the science and try to distil what GPC supplementation means for you.

What is Glycerophosphocholine (GPC)?

To start, we need to understand what GPC is. Glycerophosphocholine (GPC) is a compound found in the body that plays an important role in cell membrane function. GPC is involved in the production of acetylcholine, a neurotransmitter that helps with memory and learning, and is also a great source of choline. GPC also has antioxidant and anti-inflammatory properties, which can help protect cells from damage and disease. It is a compound that should not be overlooked. So let’s explain why.

The Benefits of GPC Supplements

Glycerophosphocholine (GPC) is a naturally-occurring compound found in the body’s cell membranes. Not only have GPC supplements been shown to improve cognitive function and memory in both healthy adults and those with Alzheimer’s disease, but they can also help protect the brain from age-related damage and improve blood flow to the brain. 

Generally speaking, GPC supplements are safe and well-tolerated, with the most common side effect being gastrointestinal upset. While there is still much to learn about the benefits of GPC supplementation for brain health, this promising new tool holds great promise for preventing age-related cognitive decline. 

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GPC For Pre-Workout and Strength Training

“It literally makes you stronger!” – Tom Hibbert – Strongman Coach  

I bet you hadn’t considered nootropics as one of your go-to pre-workout supplements; however, you might want to consider adding it to your setlist. For context, we asked strongman coach Tom Hibbert to tell us why GPC is an essential pre-workout go-to for Tom and his clients.

Tom Hibbert is an internationally renowned strength coach who lives in Southampton, UK. He has broken world records both himself as an athlete and also with clients. He walks the walk and talks the talk and is passionate about delivering results to performance-based clients. His new Winning Strength Coach certification fills the program design gap in the market.

If you can’t watch the video, here is what Tom has to say on the matter and how GPC can make you work smarter in the gym:

“One of my favourite pre-workouts is alpha glycerophosphocholine or Alpha GPC for short. The three main benefits of this pre-workout are an improvement or an increase in growth hormone output. There is an increase in focus because it’s choline, and it improves a set of choline functions. But most important for strength athletes is the improvement in contractile force. It makes you stronger. So check out GPC Liquid from Human Performance Hub, take two droplets before your next workout, and let me know how your strength gains go.”

This feels like one of the secret tips exclusively reserved for professionals, so we are pleased to share it with you all as part of our resource series.

A Word Of Warning Regarding Pre-Workout Supplements

Pre-workout supplements are over-hyped, as our founder Roan shares in this IG reel.

If you can’t watch the video, here is what Roan says:

“If you feel like you need stimulants or a pre-workout supplement, don’t take your workout. Get the rest and recovery that your body needs. When you feel rested and recovered, then go back to your workout. 

There’s a law called Yerkes Dodson Law of Performance and Arousal where the relationship between performance and arousal increase can improve performance, but only up to a certain point. And when your arousal becomes excessive, then your performance will drop. 

Workout nutrition is designed around hormones and neurotransmitters. The best pre-workout prep is to raise dopamine and acetylcholine to the desired effect for training. I’m a ginormous advocate of supporting the brain, and my go-to would be alpha GBC. I’ll put a link down below and you can do some more reading about it. I hope that helps.”

By opting for a nootropic instead, you can get many benefits without dealing with the internal rollercoaster of arousal that these pre-workout stimulants typically create.

GPC as a Source of Choline

A source of choline, glycerophosphocholine (GPC) provides acetylcholine and phosphatidylcholine, critical compounds in the body. In addition to playing a vital role in memory, learning, coordination and movement, acetylcholine also serves as a neurotransmitter on both sides of the nervous system: the sympathetic nervous system (“fight or flight”) and the parasympathetic nervous system (“rest and digest”). 

As well as the myelin coating that surrounds and protects neurons, phosphatidylcholine is an essential component of all cell membranes. Additionally, choline contributes to lung surfactant, a naturally occurring compound essential to lung health.  

For healthy fat metabolism, choline is crucial, especially with regard to the liver’s role in processing fats and making the lipoprotein particles that transport cholesterol and fat-soluble nutrients throughout the body. Choline must be present in the diet so that fats are processed efficiently and do not accumulate in the liver. 

In the human body, choline is synthesised internally, but its production is relatively limited and isn’t always sufficient to meet the needs of every individual especially if the individual needs more choline during ageing, such as supporting memory and cognition, neurological function, balanced moods, and overall physical and mental vitality. 

Choline is therefore regarded as an essential nutrient. Several foods are naturally high in choline, including egg yolks, liver, beef, peanuts, broccoli, cauliflower, and other foods from animal and vegetable sources. However, some individuals may need additional amounts, such as those provided by GPC. Choline is more concentrated in animal foods than in plant foods, and heavy alcohol consumption increases choline requirements – which might explain the slightly clouded brain fog that you experience post celebrations!  

In addition to enhancing neuron structure and function, GPC may support the nervous system and brain function due to choline’s role in acetylcholine synthesis. As a result of its chemical structure, GPC is more effective at supporting choline levels in the body than food-based choline or phosphatidylcholine, so if you are looking for insurance to ensure that you are ingesting enough GPC, then our GPC Liquid supplementation should be considered as part of your nutritional stack.

The Science: GPC Supplementation 

GPC supplementation has been shown to aid brain function, muscle function and growth hormone production and promote brain repair and recovery

The Best Way to Take GPC Supplements

The science is clear. Glycerophosphocholine (GPC) is a powerful nootropic supplement that has been shown to have a wide range of benefits for cognitive function and overall brain health. GPC supplements are most effective when taken in doses of 500-1000 mg daily, which can be taken in capsule form or as a powder or liquid, which can be mixed into water or other beverages.

Recommended Use 

GPC Liquid: As a dietary supplement, take 2 mL (approx. 2 droppers full) per day or as directed by your health 

The Side Effects of GPC Supplements

GPC is generally well-tolerated by healthy adults, with the most common side effect being mild gastrointestinal upset. However, it should be taken with caution by those with pre-existing medical conditions, and pregnant or breastfeeding women should consult with their healthcare provider before taking any nootropic supplement. 

Overall, GPC should be safe for most people, but our advice is that it is always important to talk to your doctor before starting any new supplement if you have any concerns.

Order Your GPC Liquid From Human Performance Hub Today

So that’s the tea – if you’re looking for a high-quality GPC supplement, Human Performance Hub has got you covered. Plus, our team is always available to answer any questions you might have about taking any of our supplements or offer advice on putting together the right supplement stack for your individual requirements.

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Consultations

We’re always here to help. Please book a consultation if you have any questions or want advice on nutrition, supplements or training; inquire here.

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An inflammation-fighting, immune-boosting compound

NAC is a compound that should definitely be on your radar. In this guide, we’ll explain exactly NAC (N-Acetyl-L-Cysteine), dive into the science, and explain how you can add NAC supplementation to your supplement stack.

What Is N-Acetyl-L-Cysteine?

N-Acetyl-L-Cysteine is a naturally occurring amino acid that plays an important role in the body’s detoxification process. It is effective in treating various conditions, including liver disease, bronchitis, and diabetes.

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It is also being studied for its potential to treat Alzheimer’s disease and other forms of dementia and explored as a possible treatment for a wide range of other diseases.

The Many Benefits of N-Acetyl-L-Cysteine

N-Acetyl-L-Cysteine is a powerful antioxidant that can help protect your cells from damage. This inflammation-fighting compound is beneficial for various issues, such as boosting your immune system and fighting off infection.

Proper intake of N-Acetyl-L-Cysteine can also help to boost your immune system. By improving liver function and detoxifying your body, this valuable compound helps reduce inflammation throughout your body.

N-Acetyl-L-Cysteine is also known to improve brain health and cognition. In fact, research has shown that it may even be able to halt the progression of Alzheimer’s disease.

Finally, N-Acetyl-L-Cysteine is great for overall physical wellness. It can help reduce inflammation in various parts of the body, promote better joint health, and more!

Not too bad, right? Let’s dive into the science behind N-Acetyl-L-Cysteine …

The Science: N-Acetyl-L-Cysteine

NAC is an incredibly well-researched compound with a number of clear benefits backed by science.

Liver Detoxification 

As an amino acid, NAC increases GSH levels to protect against free radical accumulation and oxidative stress, which are harmful to liver detoxification. According to research, NAC protects the liver from the damaging effects of excessive alcohol consumption and acetaminophen poisoning.

Acetaminophen poisoning can cause hepatocyte necrosis, which is a result of excessive acetaldehyde buildup and oxidative damage. Due to its high affinity for mercury, lead, and cadmium, L-Cysteine can bind to them and aid in their removal. A low level of GSH makes the liver more vulnerable to damage from these toxins.  

In short, NAC can ultimately contribute to healthier liver function, and such a vital organ is worth protecting at all costs.

Reproductive & Metabolic Health 

As a potent antioxidant, NAC is a useful adjunctive therapy for male and female infertility and reproductive health. The results of a systematic review concluded that 600 mg of NAC significantly improved sperm motility, volume, and viscosity compared to placebo. 

Another study found that supplemental NAC significantly improved insulin sensitivity in PCOS women with hyperinsulinemia. After 46 weeks of supplementation, NAC increased ovulation rate and HDL-C levels and decreased weight, BMI, fasting blood glucose, total cholesterol, LDL-C, and HOMA-IR. 

As reported in a recent in-vitro study of hyperglycemia-induced cardiomyocyte injury, NAC treatment induced similar mitochondrial energetic and cellular viability effects as metformin; however, NAC had more noticeable effects in reducing ROS production in the cytosol and mitochondria, as well as increasing CoQ10 production, which was significantly reduced by high glucose exposure.

According to a systematic review exploring the ameliorative effects of NAC on obesity-associated metabolic complications, including metabolic syndrome, it limits oxidative damage, improves pro-inflammatory responses, inhibits lipid accumulation by targeting adipogenic transcription factors, enhances insulin sensitivity by enhancing PI3K and AKT pathways in both in-vitro and in-vivo models of obesity. 

Who can argue with stronger sperm, healthier ovulation and a more optimal metabolic rate? Not us.

Lung Health 

Lung health is paramount to high performance, whether in the gym, on the sports field, or simply being able to keep up with your kids. NAC has proven benefits for this vital organ.

N-Acetyl Cysteine breaks down the sulphide bonds that thicken mucus, and, as a result, NAC improves respiratory patterns by thinning mucus viscosity. As a mucolytic drug, NAC is used in Europe to treat chronic bronchitis (CB) aggravations and improve symptoms. 

Based on a recent review, NAC was found to be well-tolerated by patients who had chronic bronchitis or chronic obstructive pulmonary disease (COPD) exacerbations and was shown to aid in mucus elimination and provide symptomatic relief from coughing, as well as resulting in significantly fewer COPD or CB aggravations, according to a meta-analysis,

 The protective effect of NAC was more apparent in those with no signs of airway obstruction. Researchers found that NAC inhibited biofilm formation, disrupted pre-existing mature and infant biofilms, and reduced bacterial growth within biofilms in biofilm-related respiratory infections, including CB, COPD, and rhinosinusitis.

In addition to biofilm formation, the researchers point out that many biofilms are resistant to antibiotics, making it necessary to use non-antibiotic therapies. 

According to animal studies, NAC has a significant antioxidative effect on airway hyperresponsiveness (AHR), which occurs in asthma when pro-inflammatory mediators and immune cells are consistently present in the airways. 

Brain & Central Nervous System Health

We all need to protect our brain health at all costs, and in our philosophy, a healthy brain is the first step to a healthy body. It has been shown that the accumulation of mercury in the brain leads to increased lipid peroxidation, mitochondrial breakdown, depletion of GSH, and protein DNA oxidation, all of which are critical factors in the development of neurodegenerative diseases. The common link between these factors is oxidative damage.

According to a review, NAC is an effective therapy for treating neurodegenerative and mental health diseases because it crosses the blood-brain barrier, provides the brain with cysteine for glutathione production, and protects neuronal mitochondria from programmed cell death, ROS, and memory loss, as well as enhances synaptic and non-synaptic activity within the mitochondrial complex.

It has also been shown that NAC has neuroprotective effects against strokes and traumatic brain injuries (TBIs), which are mediated by its ability to counter oxidative stress, free radicals, and pro-inflammatory mediators. TBI patients treated with NAC after blast exposure had significantly improved symptoms after seven days compared to those treated with placebos. 

In a pilot study, NAC supplementation for six months increased functional connectivity within the cingulate cortex in early psychosis patients compared to controls, demonstrating its effect on neuropsychiatric health. As a result, increased brain GSH through NAC supplementation may be an effective alternative to antipsychotic medications for improving functional connectivity within the brain. 

A systematic review investigated NAC’s effectiveness in treating obsessive-compulsive disorder (OCD), since it modulates the amino acid glutamate. On average, 2,400 – 3,000 mg of NAC per day for 12 weeks reduced the severity of OCD symptoms with minimal adverse effects and good tolerability. 

Muscle Recovery & Pain 

During a strenuous workout, damaging free radicals are released as a natural result of muscular contractions. The glutathione in the body scavenges free radicals diligently, while NAC quickly restores glutathione levels to normal. 

Research shows that NAC promotes muscle performance and supports efficient muscle recovery post-workout and during periods of muscle exertion because it scavenges free radicals and oxidative stress, which are related to muscle fatigue.

Oral NAC therapy significantly reduced the expression of type II collagen in chondrocytes, an indicator of osteoarthritis (OA). It inhibited ROS accumulation and proinflammatory cytokine expression in an in vivo and in vitro animal model of osteoarthritis (OA), suggesting that NAC may be an effective treatment for OA prevention. 

How to Take N-Acetyl-L-Cysteine for Optimal Results

N-Acetyl-L-Cysteine is a powerful antioxidant and anti-inflammatory supplement that has a wide range of health benefits. It is most commonly taken to improve respiratory health, but it can also help to boost cognitive function, detoxify the body, and protect the liver.

The recommended dosage of NAC is 600 mg per day, but some people may need to take up to 1,200 mg per day for optimal results.

NAC is generally well tolerated, but some people may experience side effects like nausea or headaches at high doses. If you’re interested in taking NAC, talk to your doctor first to ensure it’s safe for you and determine the best dose for your needs.

Are There Any Side Effects of Taking N-Acetyl-L-Cysteine?

N-Acetyl-L-Cysteine is a powerful antioxidant that has a wide range of potential health benefits. However, like all supplements, it is important to be aware of the potential side effects before taking them.

The most common side effect of N-Acetyl-L-Cysteine is nausea, which can usually be alleviated with food. Other potential side effects include headache, dizziness, and gastrointestinal distress.

As with any supplement, it is always best to speak with a healthcare professional before taking N-Acetyl-L-Cysteine to ensure it is right for you and to avoid any possible interactions with other medications or supplements you may be taking.

Order Your N-Acetyl L-Cysteine From Human Performance Hub Today

N-Acetyl L-Cysteine supplementation helps to detoxify the body and has many other benefits, including helping to improve memory and reducing inflammation. If you’re looking for a high-quality NAC supplement, Human Performance Hub has got you covered. 

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Further Reading

🔗 NAC / Glutathione – One of the Most Powerful Antioxidants in the Body

Our environment dictates a lot for our health; whether it be the food we eat, the air we breathe or the water we drink, it all impacts us and our health.

For many of us, the environment may put added stress on our bodies. For example, pollution in the air means we inhale all sorts of toxic chemicals, which,  once in the body, can affect many systems and the body’s cells. Ultimately this affects how we function and can lead to health issues and diseases.

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Consultations

We’re always here to help. If you have any questions or want advice on nutrition, supplements or training, please book a consultation.

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A synergistic formula offering comprehensive gastrointestinal health and function support

Introducing GI Regenerate – A New Supplement for Gut Health

GI Regenerate is a new probiotic supplement designed to support gut health. The unique blend of clinically-proven gut-supporting strains in GI Regenerate has been shown to promote digestive and immune health, making it an easy-to-take supplement that can be taken once daily with or without food.

Why Gut Health Is Important for Overall Health and Well-Being

Gut health is important for overall health and well-being, as a healthy gut can help protect against conditions like obesity, diabetes, heart disease, and inflammatory bowel disease. 

Probiotics are live bacteria and yeasts that are good for your health, especially your digestive system. Prebiotics are non-digestible fibres that act as food for probiotics, helping them to grow and flourish in the gut, assisting with overall gut health.

What Is a Leaky Gut? And How Does It Impact Gut Health

Leaky gut is a syndrome that some scientists and natural health practitioners have identified where minuscule gaps appear in the gut, allowing toxins and other compounds through. This results in constipation, bloating, gas, poor immune function, lack of focus, fatigue, and joint pain.

To prevent this, the gut lining needs to be fortified so those harmful substances cannot pass through and affect us. The GI Regenerate formula is specifically designed to do that. GI Regenerate is a natural supplement to support the gut lining, helping to stop allergens, toxins and disease from getting into the bloodstream.

Tips for Improving Gut Health

The gut is a complex system that plays a vital role in overall health and well-being. Improving gut health can be achieved by making simple lifestyle changes, such as eating a healthy diet, exercising, and reducing stress levels.

Many different supplements are available that can help improve gut health; however, it is important to speak with a healthcare professional before starting any new supplement regimen.

Our GI Regenerate supplement provides an easy way to improve gut health. The ingredients in our supplement help repair the lining of the gut, which can be damaged by inflammation, and help to increase the production of healthy bacteria in the gut, which can help to improve digestion and overall health.

How GI Regenerate Can Help Improve Your Gut Health

If you want to improve your gut health, GI Regenerate is an excellent option. This supplement can help rid your body of harmful bacteria, improve digestion, and support overall health. 

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GI Regenerate Benefits:

  • Promotes the health of the intestinal mucosa 
  • Maintains intestinal permeability by supporting the integrity of the small intestine 
  • Supports mucosal health and normal inflammatory responses 
  • Maintains healthy bowel function and promotes regularity 
  • Contributes to the health of the gut-associated immune system

Here are some tips on how to take advantage of the benefits of GI Regenerate:

  1. Start by taking GI Revive regularly for best results. The more often you take it, the better!
  2. Follow the directions that come with your product carefully. Do not overdose or take it if you have any pre-existing conditions or illnesses that could be aggravated by probiotics, such as diarrhoea or irritable bowel syndrome (IBS).
  3. Be sure to include plenty of good-quality fibre in your diet along with GI Regenerate for optimal results. Fibre helps to promote regularity and keep your gut healthy and functioning properly.
  4. Finally, drink plenty of water before and after taking GI Regenerate to help flush out toxins and maintain hydration levels in your gut.

The Science: GI Regenerate Ingredients

Our GI Regenerate supplement is formulated from best-in-class ingredients, each with its own unique offering. They include, but are not limited to:

Zinc Carnosine  

In addition to being mucosal-protective and anti-ulcerative, zinc carnosine also protects the intestinal lining. It supports tight junction integrity against damage caused by intense exercise or certain anti-inflammatory medications, including combating H pylori. 

NSAID indomethacin was shown to increase gut permeability in healthy subjects when zinc carnosine was compared to a placebo. The placebo arm experienced a threefold increase in gut permeability, while the zinc-treated group did not show any significant changes.

A study with patients with small bowel injuries caused by extended use of low-dose aspirin showed significant reductions in the number of reddened lesions and erosions/ulcers when zinc carnosine was taken for four weeks compared to untreated controls. Our formula prefers zinc carnosine, which is zinc complexed with the amino acid L-carnosine in a 1:1 ratio chelate, as it remains in stomach juice without rapid dissociation and adheres more effectively to ulcerous lesions. After that, zinc and L-carnosine are separated, and the affected tissue heals.  

L-Glutamine 

The amino acid glutamine plays a critical role in the health of intestinal cells. In addition to being their primary fuel, it is also necessary to repair and maintain high-turnover tissues such as the epithelial cells of the intestinal lining. In the body, glutamine is abundant; however, prolonged physiological or metabolic stress can cause glutamine stores to deplete. The effects of supplemental L-glutamine include immunomodulatory, anti-catabolic/anabolic, and mucosal protection of the gastrointestinal tract.

In addition to building glutathione, it may also function as an antioxidant. A variety of physiological stressors and catabolic states increase the requirement for glutamine, including trauma, infections, burns, and other physiological stressors. It has been shown that glutamine deficiency causes severe intestinal degradation, which supplementation may enhance. 

Supplementation with glutamine has been shown to reduce inflammation and GI distress caused by exercise-induced small intestinal permeability increases. Intestinal permeability must be maintained in order to prevent a “leaky gut.” Incompletely digested proteins, peptides, and other compounds may gain access to systemic circulation if intestinal permeability increases, resulting in systemic inflammation and possibly contributing to the aetiology of chronic inflammatory diseases and autoimmune diseases. 

Methylsulfonylmethane (MSM) and Quercetin 

These anti-inflammatory substances may help prevent increased intestinal permeability by reducing chronic inflammation. Aside from providing direct anti-inflammatory effects by stabilising intestinal mast cells, quercetin may also be an antioxidant that promotes tissue health.

N-Acetyl Glucosamine 

The amino acid N-acetyl glucosamine (GlcNAc) regulates inflammation in mucosal cells and aids in structural support. By supplementing with GlcNAc, glycosaminoglycans (GAGs) may be produced more effectively, supporting mucosal health and reducing intestinal permeability.

DGL, Aloe Vera, Slippery Elm, Marshmallow, Chamomile, Okra, and Cat’s Claw 

The use of each of these botanicals in gastrointestinal disorders dates back centuries. As well as supporting healthy intestinal function, these mucilaginous and relaxing herbs can promote the healing of ulcers and inflamed tissue and reduce cramping from the relaxing effect of their compounds. 

Mucin 

An intestinal epithelial cell normally secretes mucin, a glycoprotein. In addition to coating the intestinal lining, it is one of the most significant parts of the innate immune system. It serves as a front line of host defence and a breeding ground for commensal microorganisms. In addition to neutralising gastrointestinal antigens, it may also reduce inflammation and tissue damage caused by food allergies, gastrointestinal issues and dysbiosis by contributing to a healthy mucosal layer. As well as protecting epithelial cells against physical and chemical injury, mucin is a lubricant to facilitate the passage of materials through the gastrointestinal tract. 

Prune Powder and Citrus Pectin 

These two ingredients can maintain regularity without the harmful effects of herb laxatives like senna. Prunes support healthy bowel function as a natural source of sorbitol and chlorogenic acid.

The Best Way to Take GI Supplements

There are different forms of GI supplementation – however, at Human Performance Hub, we recommend powder form.

Recommended Usage and Guidelines

The suggested dose is 8g (1 tablespoon) in water in powder form in-between meal times.

The benefit of powder versus the capsule form is that the powder is easier to take and likely faster to absorb in the stomach. Personal preference will be key in determining whether you go for the capsule or powder format.

Order GI Regenerate From Human Performance Hub Today

A large part of our immune system is housed in the gastrointestinal tract, essential for digesting food and the key to preventing illness.

That is why it is essential to look after your gut health and promote a healthy microbial balance.

GI Regenerate by Human Performance Hub acts as gut health insurance, promoting overall gut health and healthy bowel movements.

Put your gut health first by ordering GI Regenerate today.

Further Reading

Wanting to dive further into the wonderful world of gut health? Check out our articles and resources on the subject:

🔗 L-glutamine benefits for your gut, brain, muscles and more…

🔗 Foundation Series: Gut and Brain – The Immune system

🔗 Leaky Gut, Gluten, and Inflammation: What’s the Connection?

🔗 Resource: GI Microbial

🔗 Resource: Digestzymes

Consultations

We’re always here to help. If you have any questions or want advice on nutrition, supplements or training, please book a consultation.